CARD ID | 586 | |
Type of strain | Targeted mutant. | |
Strain name | B6;129S4-Pargtm1Ncc/Csk | |
Internal Code | , B6;129S4-Pargtm1Ncc/Csk | |
Submitter | Unknown Unknown | |
Submitter affiliation or code | ||
Stock Type | ||
Material Transfer Conditions |
Consent to us
|
|
Production method | in-house breeding | |
Origin (In-house) | Organization | Chugai Research Institute for Medical Science Inc., National Cancer Center Research Institute |
Organization code | Csk, Ncc | |
Developer | Kou-ichi Jishage, Mitsuko Masutani | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Parg |
Gene name | Poly (ADP-ribose) glycohydrolase |
Allele symbol | Pargtm1Ncc |
Allele name | Parg,National Cancer Center Research Institute |
MGI | MGI:1347094, |
Chromosome | 14 , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
OMIM | OMIM ID: 603501 Human Gene Symbol: PARG, |
mpG2061S | 5' ctc ggc cgt ggc cgc gac aag c 3' |
mpG2318A | 5' cct ccg ctc ggc agc agg ga 3' |
Author | Atsushi Shibata, Nobuo Kamada, Ken-ichi Masumura, Takehiko Nohmi, Shizuko Kobayashi, Hirobumi Teraoka, Hitoshi Nakagama, Takashi Sugimura, Hiroshi Suzuki and Mitsuko Masutani |
Title | Parp-1 deficiency causes an increase of deletion mutations and insertions/ rearrangements in vivo after treatment with an alkylating agent |
Journal | Oncogene |
Volume | 24 |
Page | 1328-1337 |
Year | 2005 |
PMID | 15608683 |
Author | MITSUKO MASUTANI, HIROSHI SUZUKI, NOBUO KAMADA, MIHO WATANABE, OTOYA UEDA, TADASHIGE NOZAKI, KOU-ICHI JISHAGE, TAKESHI WATANABE, TETSURO SUGIMOTO, HITOSHI NAKAGAMA, TAKAHIRO OCHIYA, AND TAKASHI SUGIMURA |
Title | Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes |
Journal | Proc. Natl. Acad. Sci. USA |
Volume | 96 |
Page | 2301-2304 |
Year | 1999 |
PMID | 10051636 |
Author | T. Nohmi, M. Katoh, H. Suzuki, M. Matsui, M. Yamada, M. Watanabe, M. Suzuki, N. Horiya, O. Ueda, T. Shibuya, H. Ikeda, and T. Sofuni |
Title | A NewTransgenic Mouse Mutagenesis Test System Using Spi- and 6-Thioguanine Selections |
Journal | Environmental and Molecular Mutagenesis |
Volume | 28 |
Page | 465-470 |
Year | 1996 |
PMID | 8991079 |
Disease name, Applicable field | Metabolism, Immunology |