| CARD ID | 2971 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6D2-Dnah8em1Osb | |
| Internal Code | Dnah8 KO | |
| Submitter | Ikawa Masahito | |
| Submitter affiliation or code | Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University | |
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again. |
|
| Production method | in-house breeding | |
| Origin (In-house) | Organization | |
| Organization code | ||
| Developer | ||
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Dnah8 |
| Gene name | dynein, axonemal, heavy chain 8 |
| Allele symbol | Dnah8em1Osb |
| Allele name | dynein, axonemal, heavy chain 8; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University |
| MGI | MGI:107714, |
| Chromosome | 17 (15.71) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM |
| Author | Chunyu Liu , Haruhiko Miyata , Yang Gao , Yanwei Sha , Shuyan Tang , Zoulan Xu , Marjorie Whitfield , Catherine Patrat , Huan Wu , Emmanuel Dulioust , Shixiong Tian , Keisuke Shimada , Jiangshan Cong , Taichi Noda , Hang Li , Akane Morohoshi , Caroline Cazin , Zine-Eddine Kherraf , Christophe Arnoult , Li Jin , Xiaojin He , Pierre F Ray , Yunxia Cao , Aminata Touré , Feng Zhang , Masahito Ikawa |
| Title | Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility |
| Journal | Am J Hum Genet . |
| Volume | 107(2) |
| Page | 330-341 |
| Year | 2020 |
| PMID |
| Disease name, Applicable field |