CARD R-BASE



Mouse strain


Strain information

CARD ID 1839
Type of strain Targeted mutant.
Strain name B6;129-Tdgtm1
Internal Code Tdg kncokout mouse
Submitter Ono Tetsuya
Submitter affiliation or code Department of Cell Biology, Tohoku University School of Medicine
Stock Type
Material Transfer Conditions Others
Production method in-house breeding
Origin (In-house) Organization
Organization code
Developer
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Tdg
Gene name thymine DNA glycosylase
Allele symbol Tdg
Allele name targeted mutation 1
MGI
Chromosome 10 (39.72) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method
OMIM

PCR Primer 1
Tdg (c) 5' ACATTCCTAACTCGCTTGCTCA 3'
Tdg (wt) 5' CTCTCAACCACTGCCATCTC 3'
PCR Primer 2
Tdg (c) 5' ACATTCCTAACTCGCTTGCTCA 3'
Tdg (m) 5' CAGCCTCTGTTCCACATACACTTC 3'


References

Author Yusuke Saito, Tetsuya Ono, Naoki Takeda, Takehiko Nohmi, Masayuki Seki, Takemi Enomoto, Tetsuo Noda, Yoshihiko Uehara
Title Embryonic lethality in mismatch-specific thymine DNA glycosylase deficient mice is partially prevented by DOPS, a precursor of noradrenaline
Journal Tohoku J. Exp. Med.
Volume 226
Page 75-83
Year 2012
PMID


Disease , Applicable field information

Disease name, Applicable field Others, Molecular biology






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