| CARD ID | 312 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6;CB-Dtrtm2(lox) | |
| Internal Code | loxHB-2, | |
| Submitter | Unknown Unknown | |
| Submitter affiliation or code | ||
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
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| Production method | in-house breeding | |
| Origin (In-house) | Organization | Research Institute for Microbial Diseases, Osaka Univ. |
| Organization code | Unknown | |
| Developer | Eisuke Mekada | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Dtr(synonym:Hegf1) |
| Gene name | diphtheria toxin receptor |
| Allele symbol | Dtrtm2(lox) |
| Allele name | Dtr, targeted mutation 2 |
| MGI | MGI:96070, |
| Chromosome | 18 (15.0cM) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| GO | Gene Ontology |
| OMIM | OMIM ID: 126150 Human Gene Symbol: HBEGF, |
| Author | Ryo Iwamoto, Satoru Yamazaki, Masanori Asakura, Seiji Takashima, Hidetoshi Hasuwa, Kenji Miyado, Satoshi Adachi, Masafumi Kitakaze, Koji Hashimoto, Gerhard Raab, Daisuke Nanba, Shigeki Higashiyama, Masatsugu Hori, Michael Klagsbrun, and Eisuke Mekada |
| Title | Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function |
| Journal | PNAS |
| Volume | 100 |
| Page | 3221-3226 |
| Year | 2003 |
| PMID | 12621152 |
| Disease name, Applicable field | Dermatology, cancer, Development, Anatomy, Physiology |