CARD R-BASE



Mouse strain


Strain information

CARD ID 428
Type of strain Transgenic.
Strain name C57BL/6N-Tg(CAG-AURKA(WT))Card
Internal Code , C57BL/6N-Tg(CAG-AURKA(WT))Card
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Center for Animal Resources and Development, Kumamoto University
Organization code
Developer Misao Suzuki
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks Unknown


Gene information

Gene symbol AURKA
Gene name Aurora-kinase A (human)
Allele symbol
Allele name
MGI
Chromosome
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM OMIM ID: 603072 Human Gene Symbol: AURKA,

PCR Primer 1
primerA 5'(Aurora-A S2: aaa gag caa gca gcc cct gc)3'
primerB


References

Author Araki, K., Araki, M., Miyazaki, J. & Vassalli, P.
Title Site-Specific Recombination of a Transgene in Fertilized Eggs by Transient Expression of Cre Recombinase
Journal Proc. Natl. Acad. Sci. USA
Volume 92
Page 160-164
Year 1995
PMID 7816809
Author Bischoff, J.R., Anderson, L., Zhu, Y., Mossie, K., Ng, L., Souza, B., Schryver, B., Flanagan, P., Clairvoyant, F., Ginther, C., Chan, C.S., Novotny, M., Slamon, D.J. & Plowman, G.D.
Title A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
Journal Embo J
Volume 17
Page 3052-3065
Year 1998
PMID 9606188
Author Hogan, B., Beddington, R., Costantini, F., and Lacy, E.
Title
Journal Manipulating the Mouse Embryo: A Laboratory Manual, 2nd Edn.
Volume
Page
Year 1994
PMID


Disease , Applicable field information

Disease name, Applicable field cancer






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