CARD R-BASE



Mouse strain


Strain information

CARD ID 2201
Type of strain Transgenic.
Strain name C57BL/6Slc-Tg(NSE-betaCTFV717F,NSE-PS1P267S)
Internal Code C105F/PS1P267S
Submitter Akira Kakizuka
Submitter affiliation or code Graduate School of Biostudies, Kyoto University
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Graduate School of Biostudies, Kyoto University
Organization code
Developer Akira Kakizuka
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol PS1(P267S)
Gene name HA-tagged full-length mutant presenilin 1 (P267S)
Allele symbol
Allele name
MGI
Chromosome Unknown ,
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM
Gene symbol betaCTF(V717F)
Gene name FLAG-tagged C-terminal portion of human betaCTF with Indiana mutation (V717F)
Allele symbol
Allele name
MGI
Chromosome Unknown ,
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM

PCR Primer 1
FLAG-C105F GACTACAAGGACGACGATGACAAGGG
C105F-genotyping primer(as) TGCATCTGCTCAAAGAACTTGTAGG
PCR Primer 2
NSE-seq(s) CAAGGCTGGTCCTCATCCAT
NSE-seq(as) GTCCTCGTCCTCATAGTACT
PCR Primer 3
hPS1-LC(s) TTCGACTCCAGCAGGCATATCTC
hPS1-LC(as) AAGTGGACCTTTCGGACACAA


References

Author Norio Sasaoka, Megumi Sakamoto, Shoko Kanemori, Michiru Kan, Chihiro Tsukano, Yoshiji Takemoto, Akira kakizuka
Title Long-term Oral Administration of Hop Flower Extracts Mitigates Alzheimer Phenotypes in Mice
Journal PLOS ONE
Volume 9
Page
Year 2014
PMID


Disease , Applicable field information

Disease name, Applicable field Neurobiology






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