CARD R-BASE



Mouse strain


Strain information

CARD ID 141
Type of strain Targeted mutant.
Strain name B6.129P2-Itgb2tm1Oci
Internal Code B6.129p2-Lfa1tm1 N6
Submitter Shigeo Koyasu
Submitter affiliation or code RIKEN
Stock Type
Material Transfer Conditions Consent to us
Production method From other organizations
Origin (In-house) Organization
Organization code
Developer
Origin (From other organizations) Organization Ontario Cancer Institute
Organization code Oci
Developer Tak W. Mak
Year introduced 1998
Introduced Generation
Remarks


Gene information

Gene symbol Itgb2(Lfa1)
Gene name Integrin beta 2
Allele symbol
Allele name
MGI MGI:96611,
Chromosome 10 (41.5cM) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method
GO Gene Ontology
OMIM OMIM ID: 600065 Human Gene Symbol: ITGB2,



References

Author Rudolf Schmits, Thomas M.Kundig, Dianne M.Baker, Grace Shumaker, Jhon J.L.Simard, Gordon Duncan, Andrew Wakeham, Arda Shahinian, Annette van der Heiden, Martin F.Bachmann, Pamela S.Ohashi, Tak W.Mak, and Dennis D.Hickstein
Title LFA-1-deficient Mice Show Normal CTL Responses to Virus but Fail to Reject Immunogenic Tumor
Journal The Journal of Experimental Medicine
Volume 183
Page 1415-1426
Year 1996
PMID 8666900


Disease , Applicable field information

Disease name, Applicable field






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