CARD ID | 3010 | |
Type of strain | Targeted mutant. | |
Strain name | BRJ-Ins2em1Kuma | |
Internal Code | BRJ(BALB/c;Rag2-/-;Jak3-/-); Ins2Kuma | |
Submitter | Kume Shoen | |
Submitter affiliation or code | - | |
Stock Type | ||
Material Transfer Conditions |
Consent to us
For non-profit, please cite the following publication. Sakano D, Inoue A, Enomoto T, Imasaka M, Okada S, Yokota M, Koike M, Araki K, Kume S. Insulin2 Q104del (Kuma) Mutant Mice Develop Diabetes with Dominant Inheritance, Sci, Reports 2020. 10(1):12187 doi: 10.1038/s41598-020-68987-z. For profit-making organization, MTA is required. |
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Production method | in-house breeding | |
Origin (In-house) | Organization | Tokyo Institute of Technology |
Organization code | ||
Developer | Shoen Kume | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Ins2 |
Gene name | insulin II |
Allele symbol | Ins2em1Kuma |
Allele name | insulin II; endonuclease-mediated mutation 1, |
MGI | MGI:96573, |
Chromosome | 7 (88.00) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | |
OMIM |
Author | Airi Inoue, Takayuki Enomoto, Mai Imasaka, Seiji Okada, Mutsumi Yokota, Masato Koike, Kimi Araki, Shoen Kume |
Title | Insulin2 Q104del (Kuma) Mutant Mice Develop Diabetes with Dominant Inheritance |
Journal | Scientific Reports |
Volume | 10(1) |
Page | 12187 |
Year | 2020 |
PMID |
Disease name, Applicable field | Metabolism |