CARD R-BASE



Mouse strain


Strain information

CARD ID 2061
Type of strain Targeted mutant.
Strain name C57BL/6-TgH(XPD-TTD)
Internal Code TTD
Submitter Nishimura Emi
Submitter affiliation or code
Stock Type
Material Transfer Conditions In the following cases, you do not need to be in contact.
Production method From other organizations
Origin (In-house) Organization
Organization code
Developer
Origin (From other organizations) Organization Erasmus Medical Center Rotterdam, The Netherlands
Organization code
Developer Jan Hoeijmakers
Year introduced
Introduced Generation
Remarks Genetic backgournd:129xC57BL/6


Gene information

Gene symbol Ercc2
Gene name excision repair cross-complementing rodent repair deficiency, complementation
Allele symbol
Allele name
MGI
Chromosome 7 (9.62) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method
OMIM

PCR Primer 1
TTD p184 CTGTCCTTTTGCCGGAATAC
TTD p145(W); TTD Beta Rev(M) CCGGCTAGAGTATCTGCGG; CTCCCCTTCCTATGACATGAAC


References

Author Jan Hoeijimakers
Title Premature Aging in Mice Deficient in DNA Repair and Transcription.
Journal Science.
Volume 296
Page 1276-1279
Year 2002
PMID
Author Jan Hoeijimakers
Title A Mouse Model for the basal Transcription/DNA Repair Syndrome Trichothiodystrophy
Journal Molecular Cell.
Volume 1
Page 981-990
Year 1998
PMID


Disease , Applicable field information

Disease name, Applicable field






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