CARD ID | 2459 | |
Type of strain | Targeted mutant. | |
Strain name | B6D2-Izumo1em1(S346Stop)Osb | |
Internal Code | Izumo1 cyt | |
Submitter | Ikawa Masahito | |
Submitter affiliation or code | Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University | |
Stock Type | ||
Material Transfer Conditions |
Others
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Production method | ||
Origin (In-house) | Organization | |
Organization code | ||
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Origin (From other organizations) | Organization | |
Organization code | ||
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Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Izumo1 |
Gene name | izumo sperm-egg fusion 1 |
Allele symbol | Izumo1em1(S346Stop)Osb |
Allele name | izumo sperm-egg fusion 1, endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University |
MGI | MGI:1920706, |
Chromosome | 7 (29.39) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | |
OMIM |
genotyping Fw | GGATGGATGGAAAGGAAACG |
genotyping Rv | GGAGCCAGAAGTCAGAACCA |
Author | Young SA, Miyata H, Satouh Y, Muto M, Larsen MR, Aitken RJ, Baker MA, Ikawa M |
Title | CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility |
Journal | Reproduction |
Volume | 152 (6) |
Page | 665-672 |
Year | 2016 |
PMID |
Disease name, Applicable field |