CARD ID | 2288 | |
Type of strain | Targeted mutant. | |
Strain name | B6;129S-Acat1tm1Ishi | |
Internal Code | ACAT1KO | |
Submitter | ISHIBASHI SHUN | |
Submitter affiliation or code | Jichi Medical University | |
Stock Type | ||
Material Transfer Conditions |
Others
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Production method | in-house breeding | |
Origin (In-house) | Organization | |
Organization code | Ishi | |
Developer | Shun Ishibashi | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Acat1、SOAT1 |
Gene name | acetyl-Coenzyme A acetyltransferase 1 |
Allele symbol | Acat1tm1Ishi |
Allele name | acetyl-Coenzyme A acetyltransferase 1, targeted mutation 1, Shun Ishibashi, Jichi Medical University |
MGI | MGI:87870, |
Chromosome | 9 (29.12) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | |
OMIM |
HY30 | 5'-TCT TGT AAG CTG CTT GTA AGA GTG CC-3' |
HY31 | 5'-AGC TAG TAA GAA CAG TTC CCT TTC CC-3' |
SI-75 | 5'-GAT TGG GAA GAC AAT AGC AGG CAT GC-3' |
Author | Hiroaki Yagyu |
Title | Absence of ACAT-1 Attenuates Atherosclerosis but Causes Dry Eye and Cutaneous Xanthomatosis in Mice with Congenital Hyperlipidemia |
Journal | JBC |
Volume | 275 (28) |
Page | 21324-21330 |
Year | 2000 |
PMID |
Disease name, Applicable field |