CARD R-BASE



Mouse strain


Strain information

CARD ID 369
Type of strain Targeted mutant.
Strain name ICR;129-Hprttm1
Internal Code HPRT KO, ICR;129-Hprttm1
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions No condition
Production method From other organizations
Origin (In-house) Organization
Organization code
Developer
Origin (From other organizations) Organization Hitoshi Niwa
Organization code
Developer Department of Nutrition and Physiological chemistry, Osaka Unv. Med. Sch.
Year introduced 1999 / 3
Introduced Generation
Remarks


Gene information

Gene symbol Hprt
Gene name Hypoxanthine guanine phosphoribosyl transferase
Allele symbol Hprttm1
Allele name Hprt, targetedd mutation 1
MGI MGI:96217,
Chromosome X (16.03-17.97 cM) (XA4, XA5 band) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Other
OMIM

PCR Primer 1
primerA 5'(gcagattagcgatgatgaacc)3'
primerB 5'(cctgtccataatcagtccatga)3'


References

Author Martin Hooper, Kate Hardy, Alan Handyside, Susan Hunter & Marilyn Monk
Title HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells
Journal NATURE
Volume 326
Page 292-295
Year 1987
PMID 3821905
Author Simon Thompson, Alan R. Clarke, Angela M. Pow, Martin L. Hooper, and David W. Melton
Title Germ Line Transmission and Expression of a Corrected HPRT Gene Produced by Gene Targeting in Embryonic Stem Cells
Journal Cell
Volume 56
Page 313-321
Year 1989
PMID 2912572


Disease , Applicable field information

Disease name, Applicable field






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