CARD R-BASE



Mouse strain


Strain information

CARD ID 1974
Type of strain Targeted mutant.
Strain name C57BL/6-Ptger1tm1Sna
Internal Code EP1KO
Submitter Narumiya Shuh
Submitter affiliation or code Innovation Center for Immunoregulation Technologies and Drugs, Kyoto University Graduate School of Medicine
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Kyoto University Graduate School of Medicine, Department of pharmacology
Organization code Sna
Developer Shuh Narumiya
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Ptger1
Gene name prostaglandin E receptor 1
Allele symbol Ptger1tm1Sna
Allele name prostaglandin E receptor 1, targeted mutation 1, Shuh Natumiya, Kyoto University
MGI MGI:97793,
Chromosome 8 (40.22) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
OMIM

PCR Primer 1
TV2 gcg gag agt ccg gct aga gaa g
CV1 tga gcc tag cgg atg agg cag c
PCR Primer 2
TV2 gcg gag agt ccg gct aga gaa g
NeoEP1 cct ggg tgg aga ggc ttt tt


References

Author Matsuoka Y et al.
Title Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes
Journal Proc Natl Acad Sci U S A
Volume 100
Page 4132-4137
Year 2003
PMID


Disease , Applicable field information

Disease name, Applicable field






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