CARD ID | 399 | |
Type of strain | Targeted mutant. | |
Strain name | B6;129-Irf3tm1Isgf3gtm1 | |
Internal Code | IRF-3 KO, IRF-9 KO, B6;129-Irf3tm1Isgf3gtm1 | |
Submitter | Unknown Unknown | |
Submitter affiliation or code | ||
Stock Type | ||
Material Transfer Conditions |
Consent to us
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Production method | in-house breeding | |
Origin (In-house) | Organization | Department of Immunology, Graduate School of Medicine, The University of Tokyo |
Organization code | ||
Developer | Tadatsugu Taniguchi | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Irf3 |
Gene name | interferon regulatory factor 3 |
Allele symbol | Irf3tm1 |
Allele name | Irf3, targeted mutation 1 |
MGI | MGI:1859179, |
Chromosome | 7 , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
GO | Gene Ontology |
OMIM | OMIM ID: 603734 Human Gene Symbol: IRF3, |
Gene symbol | Isgf3g (synonym:Irf-9) |
Gene name | interferon dependent positive acting transcription factor 3 gamma |
Allele symbol | Isgf3gtm1 |
Allele name | Isgf3g, targeted mutation 1 |
MGI | MGI:107587, |
Chromosome | 14 , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
GO | Gene Ontology |
OMIM | OMIM ID: 147574 Human Gene Symbol: IRF9, |
primerA | IRF3 common: gaa cct cgg agt tat ccc gaa gg IRF3 d.s: gtt tga gtt atc cct gca ctt ggg Neo pri: tcg tgc ttt acg cta tcg ccg ctc ccg att ISGF3g: tca atg ttc cga tgt ggc agt tca aag gat c E3g: tat cga ata ctg cca gca gga acc c Neo p48: tc |
primerB |
Author | Tohru Kimura, Yuzo Kadokawa, Hisashi Harada, Masahito Matsumoto, Mitsuharu Sato, Yasuo Kashiwazaki, Masahito Tarutani, Rosemary Sok-Pin Tan, Tomohiro Takasugi, Toshifumi Matsuyama, Tak W. Mak, Shigeru Noguchi and Tadatsugu Taniguchi |
Title | Essential and non-redundant roles of p48 (ISGF3γ)and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies |
Journal | Genes to Cells |
Volume | 1 |
Page | 115-124 |
Year | 1996 |
PMID | 9078371 |
Author | Mitsuharu Sato, Hirofumi Suemori, Naoki Hata, Masataka Asagiri, Kouetsu Ogasawara, Kazuki Nakao, Takeo Nakaya, Motoya Katsuki, Shigeru Noguchi, Nobuyuki Tanaka, and Tadatsugu Taniguchi |
Title | Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction |
Journal | Immunity |
Volume | 13 |
Page | 539-548 |
Year | 2000 |
PMID | 11070172 |
Disease name, Applicable field | Immunology |