| CARD ID | 2292 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6;129S-Hmgcrtm1Ishi | |
| Internal Code | floxHMGCRKO | |
| Submitter | ISHIBASHI SHUN | |
| Submitter affiliation or code | Jichi Medical University | |
| Stock Type | ||
| Material Transfer Conditions |
Others
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| Production method | in-house breeding | |
| Origin (In-house) | Organization | |
| Organization code | Ishi | |
| Developer | Shun Ishibashi | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | Hmgcr |
| Gene name | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase |
| Allele symbol | Hmgcrtm1Ishi |
| Allele name | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase; targeted mutation 1, Shun Ishibashi |
| MGI | MGI:96159, |
| Chromosome | 13 (50.65) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | |
| OMIM |
| lox4 | 5'-GTC GAC GTT GAA TCC TCT TGT CAG AC-3' |
| xho3' | 5'-CAA AGC AGA CAT GAG ACT ATT C-3' |
| Author | Shuichi Nagashima |
| Title | Liver-Specific Deletion of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Causes Hepatic Steatosis and Death |
| Journal | Arterioscler Thromb Vasc Biol. |
| Volume | 32 (8) |
| Page | 1824-1831 |
| Year | 2012 |
| PMID |
| Disease name, Applicable field |