| CARD ID | 2692 | |
| Type of strain | Targeted mutant. | |
| Strain name | C57BL/6N-Upp1tm3Mtb;Tymptm3Mtb | |
| Internal Code | C57BL/6N-TPtm3Mtb/TPtm3Mtb:UPtm3Mtb/UPtm3Mtb | |
| Submitter | Masatatsu Yamamoto | |
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| Material Transfer Conditions |
Consent to us
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| Origin (In-house) | Organization | |
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| Origin (From other organizations) | Organization | |
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| Remarks | ||
| Gene symbol | Upp1 |
| Gene name | uridine phosphorylase 1 |
| Allele symbol | Upp1tm3Mtb |
| Allele name | uridine phosphorylase 1, targeted mutation 3, |
| MGI | MGI:1097668, |
| Chromosome | 11 (6.13) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM |
| Gene symbol | Tymp |
| Gene name | thymidine phosphorylase |
| Allele symbol | Tymptm3Mtb |
| Allele name | thymidine phosphorylase, targeted mutation 3, |
| MGI | MGI:1920212, |
| Chromosome | 15 (44.86) , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | Electroporation |
| OMIM |
| Tpf | GAGCGCTGTAACCCGACCCT |
| Tpr | TATCACCGCGTGCACGAAGTTTC |
| Tpf | GAGCGCTGTAACCCGACCCT |
| Neo | CCGATTCGCAGCGCATCGCC |
| UPG2 | CAAAGCTGAGGCCCAACTGCCATGG |
| UPG3 | CCTTGGACTTCCATTCACAGCTGCG |
| PGK3 | CCTGAAGAACGAGATCAGCAGCCTC |
| UPG4 | AGCTCTTGCTCCTTCGCCTGCTTGC |
| Author | Misako Haraguchi, Hiroaki Tsujimoto, Masakazu Fukushima, Itsuro Higuchi, Hideto Kuribayashi, Hideo Utsumi, Atsuo Nakayama, Yoshio Hashizume, Junko Hirato, Hiroki Yoshida, Hiromitsu Hara, Shinjiro Hamano, Hiroaki Kawaguchi, Tatsuhiko Furukawa, Kohei Miyazono, Fuyuki Ishikawa, Hideo Toyoshima, Tadashi Kaname, Masaharu Komatsu, Zhe-Sheng Chen, Takenari Gotanda, Tokushi Tachiwada1, Tomoyuki Sumizawa, Kazutaka Miyadera, Mitsuhiro Osame, Hiroki Yoshida, Tetsuo Noda, Yuji Yamada and Shin-ichi Akiyama |
| Title | Targeted Deletion of Both Thymidine Phosphorylase and Uridine Phosphorylase and Consequent Disorders in Mice |
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| PMID |
| Disease name, Applicable field | cancer |