CARD ID | 255 | |
Type of strain | Targeted mutant. | |
Strain name | C.129(B6)-Dsg3tm1Stan | |
Internal Code | BALB/c-[Ko]Dsg3 N11, C.129(B6)-DSg3tm1Stan N11 | |
Submitter | Shigeo Koyasu | |
Submitter affiliation or code | RIKEN | |
Stock Type | ||
Material Transfer Conditions |
Consent to us
|
|
Production method | From other organizations | |
Origin (In-house) | Organization | |
Organization code | ||
Developer | ||
Origin (From other organizations) | Organization | University of Pennsylvania |
Organization code | Stan | |
Developer | John R. Stanley | |
Year introduced | 1999 / 5 | |
Introduced Generation | N0 | |
Remarks |
Gene symbol | Dsg3 |
Gene name | desmoglein 3 |
Allele symbol | |
Allele name | |
MGI | MGI:99499, |
Chromosome | 18 , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | |
GO | Gene Ontology |
OMIM | OMIM ID: 169615 Human Gene Symbol: DSG3, |
primerA | Sequence of primers used in reaction primer name(amplify Neo gene: 280bp) M11:5'-CTTgggTggAgAggCTATTCggCT M12:5'-AggTgAgATgACAggAgATCCTgCCC |
primerB | (amplify Dsg3 gene include intron:442bp) M13:5'-ATgACCTgCCTCTTCCCTAgAgCCTT M14:5'-AggCATgCAgAgTTCTTAgCTATATT |
Author | Peter J. Koch, My G. Mahoney, Hiroyasu Ishikawa, Leena Pulkkinen, Jouni Uitto, Leonard Shultz, George F. Murphy, Diana Whitaker-Menezes, and John R. Stanley |
Title | Targeted Disruption of the Pemphigus Vulgaris Antigen (Desmoglein 3) Gene in Mice Causes Loss of Keratinocyte Cell Adhesion with a Phenotype Similar to Pemphigus Vulgaris |
Journal | The Journal of Cell Biology |
Volume | 137 |
Page | 1091-1102 |
Year | 1997 |
PMID | 9166409 |
Disease name, Applicable field | Dermatology, Development |