CARD R-BASE



Mouse strain


Strain information

CARD ID 1193
Type of strain Targeted mutant.
Strain name B6;CB-Ttrtm2(hTTR)Imeg
Internal Code TtrhTTR/hTTR
Submitter Ken-ichi YAMAMURA
Submitter affiliation or code Center for Animal Resources and Development Kumamoto University
Stock Type
Material Transfer Conditions Consent to us
1193 is a line in which a human wild TTR cDNA is inserted into the mouse Ttr locus. All embryos were collected by mating between male heterozygous mice and wild type female mice. Thus, genotypes of these embryos are either heterozygous or wild type. Please see the manuscript by Zhao et al. 2008 and hTTR KI genotyping.
Production method in-house breeding
Origin (In-house) Organization Division of Developmental Genetics, IMEG
Organization code Imeg
Developer Li Zhenghua
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Ttr
Gene name transthyretin
Allele symbol Ttrtm2(hTTR)Imeg
Allele name targeted mutation 2, Institute of Molecular Embryology and Genetics
MGI MGI:98865,
Chromosome 18 (7) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
OMIM

PCR Primer 1
A9-s 5'-CGT AGA GCG AGT GTT CCG-3'
sp-A 5'-CAG TGT ATA TCA TTG TAA CC-3'


Disease , Applicable field information

Disease name, Applicable field Metabolism, Neurobiology, Dermatology, Anatomy


EGTC

EGTC番号




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