| CARD ID | 571 | |
| Type of strain | Transgenic. | |
| Strain name | C57BL/6-Tg(CLCNKB-WNK4D564A | |
| Internal Code | mutant WNK4 transgenic mice, C57BL/6-Tg(CLCNKB-WNK4564A | |
| Submitter | Unknown Unknown | |
| Submitter affiliation or code | ||
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
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| Production method | in-house breeding | |
| Origin (In-house) | Organization | Tokyo Medical & Dental University |
| Organization code | none | |
| Developer | Uchida Shinichi | |
| Origin (From other organizations) | Organization | |
| Organization code | ||
| Developer | ||
| Year introduced | ||
| Introduced Generation | ||
| Remarks | ||
| Gene symbol | WNK4 |
| Gene name | human WNK4 (lysine deficient protein kinase 4), D564A(Aan aspartic acid-to-alanine substitution at codon 564) |
| Allele symbol | |
| Allele name | |
| MGI | |
| Chromosome | Unknown , |
| Gene classification | Gene to express(transgenic) |
| Method | MicroInjection |
| OMIM | OMIM ID: 601844 Human Gene Symbol: WNK4, |
| hWNK4seqPr2(tg-se) | 5'-ATC GTC CGC TTC TAT GAT TC-3' |
| hWNK4R(tg-an) | 5'-TCG CAC TTG AGA TCC CGG TG-3' |
| Author | Kozue Yamauchi, Sung-Sen Yang, Akihito Ohta, Eisei Sohara, Tatemitsu Rai, Sei Sasaki, Shinichi Uchida |
| Title | Apical localization of renal K channel was not altered in mutant WNK4 transgenic mice |
| Journal | Biochemical and Biophysical Research Communications |
| Volume | 332 |
| Page | 750-755 |
| Year | 2005 |
| PMID | 15907795 |
| Disease name, Applicable field | Physiology |