CARD ID | 139 | |
Type of strain | Transgenic., Targeted mutant. | |
Strain name | STOCK-Rag2tm1WumTg(Tcra)Wum | |
Internal Code | (B6 x BALB/c x 129)Rag2tm1-TgN(TCR alpha) | |
Submitter | Shigeo Koyasu | |
Submitter affiliation or code | RIKEN | |
Stock Type | ||
Material Transfer Conditions |
Consent to us
|
|
Production method | From other organizations | |
Origin (In-house) | Organization | Wum : Washington Univ Sch Med |
Organization code | Wum | |
Developer | K. M. Murphy | |
Origin (From other organizations) | Organization | Harvard Medical School |
Organization code | Wum | |
Developer | ||
Year introduced | 1994 | |
Introduced Generation | ||
Remarks |
Gene symbol | Tcra |
Gene name | T-cell receptor alpha chain |
Allele symbol | |
Allele name | |
MGI | MGI:98553, |
Chromosome | |
Gene classification | Gene to express(transgenic) |
Method | Other Homologous,Nonhomologous |
GO | Gene Ontology |
OMIM |
Gene symbol | Rag2 |
Gene name | Recombination-activating gene 2 |
Allele symbol | |
Allele name | |
MGI | MGI:98553, |
Chromosome | 2 (56.0cM) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Other Homologous,Nonhomologous |
GO | Gene Ontology |
OMIM |
Author | Shigeo Koyasu, Linda K. Clayton, Adam Lerner, Hans Heiken, Alysia Parkes and Ellis L. Reinherz |
Title | Pre-TCR signaling components trigger transcriptional activation of a rearranged TCRα gene locus and silencing of the pre-TCRα locus: implications for intrathymic differentiation |
Journal | International Immunology |
Volume | 9 |
Page | 1475-1480 |
Year | 1997 |
PMID | 9352352 |
Disease name, Applicable field |