CARD ID | 293 | |
Type of strain | Targeted mutant. | |
Strain name | B6;129-Mdktm1 | |
Internal Code | MK knockout mouse, MK knockout mouse (C57BL6J/129SV) | |
Submitter | Unknown Unknown | |
Submitter affiliation or code | ||
Stock Type | ||
Material Transfer Conditions |
Consent to us
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Production method | in-house breeding | |
Origin (In-house) | Organization | Department of Biochemistry, Nagoya University, Graduate School of Medicine |
Organization code | ||
Developer | Takashi Muramatsu | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Mdk |
Gene name | Midkine |
Allele symbol | Mdktm1 |
Allele name | Mdk, targeted mutation 1 |
MGI | MGI:96949, |
Chromosome | 2 (53.0cM) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | |
GO | Gene Ontology |
OMIM | OMIM ID: 162096 Human Gene Symbol: MDK, |
primerA | 5'(TAACC,CAggT,TTTAC,CCCTA)3' |
primerB | 5'(CTCCA,AATTC,CTTCC,TTCTT,CCAg)3' |
Author | Mitsuru Horiba, Kenji Kadomatsu, Eishin Nakamura, Hisako Muramatsu, Shinya Ikematsu, Sadatoshi Sakuma, Kenji Hayashi, Yukio Yuzawa, Seiichi Matsuo, Masafumi Kuzuya, Tadashi Kaname, Makoto Hirai, Hidehiko Saito, and Takashi Muramatsu |
Title | Neointima formation in a restenosis model is suppressed in midkine-deficient mice |
Journal | The Journal of Clinical Investigation |
Volume | 105 |
Page | 489-495 |
Year | 2000 |
PMID | 10683378 |
Author | Eishin Nakamura, Kenji Kadomatsu, Shigeki Yuasa, Hisako Muramatsu, Takayoshi Mamiya, Toshitaka Nabeshima, Qi-Wen Fan, Kazuhiro Ishiguro, Tadahiko Igakura, Shuichiro Matsubara, Tadashi Kaname, Mitsuru Horiba, Hidehiko Saito and Takashi Muramatsu |
Title | Disruption of the midkine gene (Mdk) resulted in altered expression of a calcium binding protein in the hippocampus of infant mice and their abnormal behaviour |
Journal | Genes to Cells |
Volume | 3 |
Page | 811-822 |
Year | 1998 |
PMID | 10096022 |
Author | Waichi Sato, Kenji Kadomatsu, Yukio Yuzawa, Hisako Muramatsu, Nigishi Hotta, Seiichi Matsuo, and Takashi Muramatsu |
Title | Midkine Is Involved in Neutrophil Infiltration into the Tubulointerstitium in Ischemic Renal Injury |
Journal | The Journal of Immunology |
Volume | 167 |
Page | 3463-3469 |
Year | 2001 |
PMID | 11544339 |
Disease name, Applicable field | Development |