CARD R-BASE



Mouse strain


Strain information

CARD ID 222
Type of strain Targeted mutant.
Strain name C57BL/6-Cdkn1btm1
Internal Code p27KO, p27 knockout
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Nippon Roche Research Center
Organization code Unknown
Developer Keiko Nakayama
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Cdkn1b
Gene name Cyclin-dependent kinase inhibitor 1B (P27)
Allele symbol Cdkn1btm1
Allele name Cdkn1b, targeted mutation 1
MGI MGI:104565,
Chromosome 6 ,
Gene classification Targeted or trapped gene(knockout etc.)
Method
GO Gene Ontology
OMIM OMIM ID: 600778 Human Gene Symbol: CDKN1B,



References

Author Keiko Nakayama, Noriko Ishida, Michiko Shirane, Akira Inomata, Tomoaki Inoue, Nobuyuki Shishido, Ikuo Horii, Dennis Y. Loh, and Kei-ichi Nakayama
Title Mice Lacking p27Kip1 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors
Journal Cell
Volume 85
Page 707-720
Year 1996
PMID 8646779


Disease , Applicable field information

Disease name, Applicable field Neurobiology, cancer, Development






Copyright @ 2021 Kumamoto University. All rights reserved.