CARD ID | 3096 | |
Type of strain | Targeted mutant. | |
Strain name | C57BL/6J-Hmgcs2em1 | |
Internal Code | Hmgcs2 KO | |
Submitter | Yuichiro Arima | |
Submitter affiliation or code | International Research Center for Medical Science(IRCMS), Kumamoto University | |
Stock Type | ||
Material Transfer Conditions |
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Production method | in-house breeding | |
Origin (In-house) | Organization | Kumamoto University |
Organization code | ||
Developer | Arima Yuichiro | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Hmgcs2 |
Gene name | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 |
Allele symbol | Hmgcs2em1 |
Allele name | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2; endonuclease-mediated mutation 1, |
MGI | MGI:101939, |
Chromosome | |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | |
OMIM |
Primer1 | ggtgcttgtctgggagtga |
Primer2 | cttagagatgcagcggcttt |
Author | Yuichiro Arima, Yoshiko Nakagawa, Toru Takeo, Toshifumi Ishida, Toshihiro Yamada, Shinjiro Hino, Mitsuyoshi Nakao, Sanshiro Hanada, Terumasa Umemoto, Toshio Suda, Tetsushi Sakuma, Takashi Yamamoto, Takehisa Watanabe, Katsuya Nagaoka, Yasuhito Tanaka, Yumiko K Kawamura, Kazuo Tonami, Hiroki Kurihara, Yoshifumi Sato, Kazuya Yamagata, Taishi Nakamura, Satoshi Araki, Eiichiro Yamamoto, Yasuhiro Izumiya, Kenji Sakamoto, Koichi Kaikita, Kenichi Matsushita, Koichi Nishiyama, Naomi Nakagata, Kenichi Tsujita |
Title | Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation |
Journal | Nature metabolism |
Volume | 3 |
Page | 196–210 |
Year | 2021 |
PMID | 33619377 |
Disease name, Applicable field | Digestive Disorders, Metabolism, Development, Behavior |