CARD ID | 1585 | |
Type of strain | Targeted mutant. | |
Strain name | B6;129-Tnnt2tm2Mmto | |
Internal Code | B6;129-Tnnt2tm2Mmto | |
Submitter | Morimoto Sachio | |
Submitter affiliation or code | - | |
Stock Type | ||
Material Transfer Conditions |
Consent to us
|
|
Production method | in-house breeding | |
Origin (In-house) | Organization | Kyushu University |
Organization code | 不明 | |
Developer | Sachio Morimoto | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Tnnt2 |
Gene name | troponin T2, cardiac |
Allele symbol | |
Allele name | |
MGI | MGI:104597, |
Chromosome | 1 (60.0) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
OMIM | OMIM ID: 601494 Human Gene Symbol: CMD1D, |
TNT F2 | 5'CCT AAG CCC CAG ACC TAT GC |
TNT R2 | 5' GGT TCC TCC CCG TCC C |
Author | Wang et al. |
Title | Up-regulation of type 2 iodothyronine deiodinase in dilated cardiomyopathy. |
Journal | Cardiovasc. Res. |
Volume | 87(4) |
Page | 636-646 |
Year | 2010 |
PMID |
Author | Zhan et al. |
Title | Therapeutic effect of {beta}-adrenoceptor blockers using a mouse model of dilated cardiomyopathy with a troponin mutation. |
Journal | Cardiovasc. Res. |
Volume | 84(1) |
Page | 64-71 |
Year | 2009 |
PMID |
Author | Sfichi-Duke et al. |
Title | Cardiomyopathy-causing deletion K210 in cardiac troponin T alters phosphorylation propensity of sarcomeric proteins. |
Journal | J. Mol. Cell. Cardiol. |
Volume | 48(5) |
Page | 934-942 |
Year | 2010 |
PMID |
Author | Du et al. |
Title | Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation. |
Journal | Circ. Res. |
Volume | 101(2) |
Page | 185-194 |
Year | 2007 |
PMID |
Disease name, Applicable field | Physiology, Hematology |