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CARD Mouse Bank

Mouse strain

Strain information

CARD ID 3072
Type of strain Targeted mutant.
Strain name B6D2-Iqcaem1Osb
Internal Code Iqca KO
Submitter Ikawa Masahito
Submitter affiliation or code Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University
Stock Type
Material Transfer Conditions Consent to us
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.
Production method in-house breeding
Origin (In-house) Organization
Organization code
Origin (From other organizations) Organization
Organization code
Year introduced
Introduced Generation

Gene information

Gene symbol Iqca
Gene name IQ motif containing with AAA domain
Allele symbol Iqcaem1Osb
Allele name IQ motif containing with AAA domain; endonuclease mediated mutation 1, Research Institute for Microbial Diseases, Osaka
MGI MGI:1922168,
Chromosome 1 (45.08) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation


Author Jiang Sun, Yonggang Lu, Kaori Nozawa, Zoulan Xu, Akane Morohoshi, Julio M Castaneda, Taichi Noda, Haruhiko Miyata, Ferheen Abbasi, Hossam H Shawki, Satoru Takahashi, Darius J Devlin, Zhifeng Yu, Ryan M Matzuk, Thomas X Garcia, Martin M Matzuk, Masahito Ikawa.
Title CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction
Journal Biology of Reproduction.
Volume 103(2)
Page 183-194
Year 2020 Aug 4

Disease , Applicable field information

Disease name, Applicable field

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