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CARD Mouse Bank


Mouse strain


Strain information

CARD ID 312
Type of strain Targeted mutant.
Strain name B6;CB-Dtrtm2(lox)
Internal Code loxHB-2,
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Research Institute for Microbial Diseases, Osaka Univ.
Organization code Unknown
Developer Eisuke Mekada
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Dtr(synonym:Hegf1)
Gene name diphtheria toxin receptor
Allele symbol Dtrtm2(lox)
Allele name Dtr, targeted mutation 2
MGI MGI:96070,
Chromosome 18 (15.0cM) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
GO Gene Ontology
OMIM OMIM ID: 126150 Human Gene Symbol: HBEGF,



References

Author Ryo Iwamoto, Satoru Yamazaki, Masanori Asakura, Seiji Takashima, Hidetoshi Hasuwa, Kenji Miyado, Satoshi Adachi, Masafumi Kitakaze, Koji Hashimoto, Gerhard Raab, Daisuke Nanba, Shigeki Higashiyama, Masatsugu Hori, Michael Klagsbrun, and Eisuke Mekada
Title Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function
Journal PNAS
Volume 100
Page 3221-3226
Year 2003
PMID 12621152


Disease , Applicable field information

Disease name, Applicable field Dermatology, cancer, Development, Anatomy, Physiology






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