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CARD Mouse Bank


Mouse strain


Strain information

CARD ID 2293
Type of strain Targeted mutant.
Strain name B6;129S-Fdft1,sup>tm1Ishi
Internal Code floxSSKO
Submitter ISHIBASHI SHUN
Submitter affiliation or code Jichi Medical University
Stock Type
Material Transfer Conditions Others
Production method in-house breeding
Origin (In-house) Organization
Organization code Ishi
Developer Shun Ishibashi
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Fdft1
Gene name Farnesyl diphosphate farnesyl transferase 1
Allele symbol Fdft1,sup>tm1Ishi
Allele name Farnesyl diphosphate farnesyl transferase 1, targeted mutation 1,
MGI MGI:102706,
Chromosome 14 (33.24) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method
OMIM

PCR Primer 1
R70 5'-TTG ACT GTC AGC AGC ATG TC-3'
TK56 5'-TGC CAT CAC CTT CAT TGC AC-3'
PCR Primer 2
Neo1285 5'-AGG ATC TCG TCG TGA CCC ATG GCG A-3'
Neo1485 5'-GAG CGG CGA TAC CGT AAA GCA CGA GG-3'


References

Author Shuichi Nagashima
Title Plasma cholesterol-lowering and transient liver dysfunction in mice lacking squalene synthase in the liver.
Journal JLR
Volume 56 (5)
Page 998-1005
Year 2015
PMID


Disease , Applicable field information

Disease name, Applicable field






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