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CARD Mouse Bank


Mouse strain


Strain information

CARD ID 2292
Type of strain Targeted mutant.
Strain name B6;129S-Hmgcrtm1Ishi
Internal Code floxHMGCRKO
Submitter ISHIBASHI SHUN
Submitter affiliation or code Jichi Medical University
Stock Type
Material Transfer Conditions Others
Production method in-house breeding
Origin (In-house) Organization
Organization code Ishi
Developer Shun Ishibashi
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Hmgcr
Gene name 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Allele symbol Hmgcrtm1Ishi
Allele name 3-hydroxy-3-methylglutaryl-Coenzyme A reductase; targeted mutation 1, Shun Ishibashi
MGI MGI:96159,
Chromosome 13 (50.65) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method
OMIM

PCR Primer 1
lox4 5'-GTC GAC GTT GAA TCC TCT TGT CAG AC-3'
xho3' 5'-CAA AGC AGA CAT GAG ACT ATT C-3'


References

Author Shuichi Nagashima
Title Liver-Specific Deletion of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Causes Hepatic Steatosis and Death
Journal Arterioscler Thromb Vasc Biol.
Volume 32 (8)
Page 1824-1831
Year 2012
PMID


Disease , Applicable field information

Disease name, Applicable field






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