CARD R-BASE

Home - Type of strain - Disease - Gene - Reference - Search - Japanese
CARD Mouse Bank


Mouse strain


Strain information

CARD ID 2094
Type of strain Targeted mutant.
Strain name B6;129-L3mbtl3tm1Tmiy
Internal Code MBT-1+/-
Submitter Miyazaki Toru
Submitter affiliation or code Lab of Molecular Biomedicine for Pathogenesis, Center for Disease Biology and Integrative Medicine (CDBIM), The University of Tokyo
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization The University of Tokyo
Organization code Tmiy
Developer Toru Miyazaki
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol L3mbtl3(synonym: MBT-1)
Gene name l(3)mbt-like 3 (Drosophila)
Allele symbol L3mbtl3tm1Tmiy
Allele name l(3)mbt-like 3 (Drosophila), targeted mutation 1, Toru Miyazaki, the University of Tokyo
MGI MGI:2143628,
Chromosome 10 (13.67) (10A4) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
OMIM

PCR Primer 1
MBT-1 F ATC CCG TCA GGC TTT CGA GTT GGG
MBT-1 R ATC CTC CTG CAC CAC CTC CTA AGA
PCR Primer 2
RV13 GTA TCC ATC ATG GCT GAT GCA A
RV14 AAC GCT ATG TCC TGA TAG CGG T


References

Author Arai S, Miyazaki T
Title Impaired maturation of myeloid progenitors in mice lacking novel Polycomb group protein MBT-1.
Journal EMBO J
Volume 24
Page 1863-1873
Year 2005
PMID


Disease , Applicable field information

Disease name, Applicable field Development, Immunology, cancer






Copyright @ 2021 Kumamoto University. All rights reserved.