CARD R-BASE



Mouse strain


Strain information

CARD ID 2029
Type of strain Transgenic.
Strain name C57BL/6-Tg(CD46)1Ts
Internal Code CD46Tg
Submitter Seya Tsukasa
Submitter affiliation or code Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University
Stock Type
Material Transfer Conditions Others
Production method in-house breeding
Origin (In-house) Organization Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaidou University
Organization code
Developer Tsukasa Seya
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol CD46
Gene name CD46molecule, complement regulatory protein
Allele symbol Tg(CD46)1Ts
Allele name transgene insertion 1, Timothy Stewart
MGI
Chromosome Unknown ,
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM

PCR Primer 1
CD46-exon-se gcc agt tca tct ttt gac tct att aa
CD46-exon-as cag cat atc cct gct tta ata caa c


References

Author Shingai M, Inoue N, Okuno T, Okabe M, Akazawa T, Miyamoto Y, Ayata M, Honda K,
Title Wild-type measles virus infection in human CD46/CD150-transgenic mice: CD11c-positive dendritic cells establish systemic viral infection.
Journal J Immunol.
Volume 175(5)
Page 3252-61
Year 2005 Sep 1
PMID
Author Miyagawa S, Mikata S, Tanaka H, Ikawa M, Kominami K, Seya T, Nishimune Y, Shirakura R, and Okabe M.
Title The regulation of membrane cofactor protein (CD46) expression by the 3' untranslated region in transgenic mice.
Journal Biochem. Biophys. Res. Commun.
Volume 233
Page 829-833
Year 1997
PMID
Author Seya T, Hara T, Matsumoto M, and Akedo H.
Title Quanatitative analysis of membrane cofactor protein (MCP) of complement: High expression of MCP on human leukemia cell lines, which is down-regulated during cell-differentiation.
Journal J. Immunol.
Volume 145
Page 238-245.
Year 1990
PMID


Disease , Applicable field information

Disease name, Applicable field Immunology






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