| CARD ID | 254 | |
| Type of strain | Targeted mutant. | |
| Strain name | B6.129X1-DSg3tm1Stan | |
| Internal Code | C57BL/6-[Ko]Dsg3 N11, B6.129X1-Dsg3tm1Stan N11 | |
| Submitter | Shigeo Koyasu | |
| Submitter affiliation or code | RIKEN | |
| Stock Type | ||
| Material Transfer Conditions |
Consent to us
|
|
| Production method | From other organizations | |
| Origin (In-house) | Organization | |
| Organization code | ||
| Developer | ||
| Origin (From other organizations) | Organization | University of Pennsylvania |
| Organization code | Stan | |
| Developer | John R. Stanley | |
| Year introduced | 1999 / 5 | |
| Introduced Generation | N0 | |
| Remarks | ||
| Gene symbol | Dsg3 |
| Gene name | desmoglein 3 |
| Allele symbol | |
| Allele name | |
| MGI | MGI:99499, |
| Chromosome | 18 , |
| Gene classification | Targeted or trapped gene(knockout etc.) |
| Method | |
| GO | Gene Ontology |
| OMIM | OMIM ID: 169615 Human Gene Symbol: DSG3, |
| primerA | Sequence of primers used in reaction primer name(amplify Neo gene: 280bp) M11:5'-CTTgggTggAgAggCTATTCggCT M12:5'-AggTgAgATgACAggAgATCCTgCCC |
| primerB | (amplify Dsg3 gene include intron:442bp) M13:5'-ATgACCTgCCTCTTCCCTAgAgCCTT M14:5'-AggCATgCAgAgTTCTTAgCTATATT |
| Author | Peter J. Koch, My G. Mahoney, Hiroyasu Ishikawa, Leena Pulkkinen, Jouni Uitto, Leonard Shultz, George F. Murphy, Diana Whitaker-Menezes, and John R. Stanley |
| Title | Targeted Disruption of the Pemphigus Vulgaris Antigen (Desmoglein 3) Gene in Mice Causes Loss of Keratinocyte Cell Adhesion with a Phenotype Similar to Pemphigus Vulgaris |
| Journal | The Journal of Cell Biology |
| Volume | 137 |
| Page | 1091-1102 |
| Year | 1997 |
| PMID | 9166409 |
| Disease name, Applicable field | Dermatology, Development |