CARD ID | 240 | |
Type of strain | Transgenic. | |
Strain name | BXD-Tg(Hpoc-OSF1) | |
Internal Code | Bone-rich mouse, HPoc-Hosf1-6 | |
Submitter | Unknown Unknown | |
Submitter affiliation or code | ||
Stock Type | ||
Material Transfer Conditions |
Consent to us
|
|
Production method | in-house breeding | |
Origin (In-house) | Organization | Kyoto Pref. Univ, Med., RINDG, DBMG |
Organization code | ||
Developer | Harufumi Masuda & T.Hashimoto-Gotoh | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | OSF1(=PTN) |
Gene name | Pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)(Human) |
Allele symbol | |
Allele name | |
MGI | |
Chromosome | Unknown , |
Gene classification | Gene to express(transgenic) |
Method | |
OMIM | OMIM ID: 162095 Human Gene Symbol: PTN, |
primerA | 5'(GAAAATTTGCAGCTGCCTTC)3' OSF_U246 |
primerB | 3'(AACTCGTAGACTGAAGACC)5' TGL542 |
Author | Haruchika Masuda, Atsushi Tasujimura, Makoto Yoshioka, Yuji Arai, Yoshinori Kuboki, Tsunehiro Mukai, Toshitaka Nakamura, Hajime Tsuji, Masao Nakagawa, and Tamotsu Hashimoto-Gotoh |
Title | Bone Mass Loss Due to Estrogen Deficiency Is Compensated in Transgenic Mice Overexpressing Human Osteoblast Stimulating Factor-11 |
Journal | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
Volume | 238 |
Page | 528-533 |
Year | 1997 |
PMID | 9299545 |
Author | Hashimoto-Gotoh, T., Masuda, H., Yamaguchi, M., Tsujimura, A., Ohnishi, H., Imai, S., Inoue, K., Nakamura, T., Hirasawa, T. and Nakagawa, M. |
Title | Feasibility of gene therapy using human OSF1 against osteoporosis |
Journal | Osteoporosis Japan |
Volume | 9 |
Page | 5-7 |
Year | 2001 |
PMID |
Disease name, Applicable field | Metabolism |