CARD ID | 404 | |
Type of strain | Targeted mutant. | |
Strain name | B6;129Sv-Irf2tm1Prkrtm1 | |
Internal Code | B6, B6;129Sv-Irf2tm1Prkrtm1 | |
Submitter | Unknown Unknown | |
Submitter affiliation or code | ||
Stock Type | ||
Material Transfer Conditions |
Consent to us
|
|
Production method | From other organizations | |
Origin (In-house) | Organization | |
Organization code | ||
Developer | ||
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | 1997 | |
Introduced Generation | ||
Remarks |
Gene symbol | Prkr |
Gene name | protein kinase, interferon-inducible double stranded RNA dependent |
Allele symbol | Prkrtm1 |
Allele name | Prkr, targeted mutation 1 |
MGI | MGI:1353449, |
Chromosome | 17 , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | |
GO | Gene Ontology |
OMIM | OMIM ID: 176871 Human Gene Symbol: EIF2AK2, |
Gene symbol | Irf2 |
Gene name | interferon regulatory factor-2 |
Allele symbol | Irf2tm1 |
Allele name | Irf2, targeted mutation 1 |
MGI | MGI:96591, |
Chromosome | 8 , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | |
GO | Gene Ontology |
OMIM | OMIM ID: 147576 Human Gene Symbol: IRF2, |
primerA | Irf2 F2A4: cgg tag act ctg aag gcg ttg tt Irf2 F2S3: ttc cag atc ccc tgg atg cat gc Irf2 F2N: aac gca cgg gtg ttg ggt cgt ttg PKR-S common: ttt taa agc aga tgg tcc agg ag PKR as WT: ctg agg cac act cag cct ttt at PKR neo: att cgc agc gca tcg cct tct at |
primerB | Irf2 F2A4: cgg tag act ctg aag gcg ttg tt Irf2 F2S3: ttc cag atc ccc tgg atg cat gc Irf2 F2N: aac gca cgg gtg ttg ggt cgt ttg PKR-S common: ttt taa agc aga tgg tcc agg ag PKR as WT: ctg agg cac act cag cct ttt at PKR neo: att cgc agc gca tcg cct tct at |
Author | Toshifumi Matsuyama, Tohru Kimura, Motoo Kitagawa, Klaus Pfeffer, Takatoshi Kawakami, Nobumasa Watanabe, Thomas M. Kundig, Ryuichi Amakawa, Kenji Kishihara, Andrew Wakeham, Julia Potter, Caren L. Furlonger, Arumugavadivel Narendran, Haruhiko Suzuki, Pamela S. Ohashi, Christopher J. Paige, Tadatsugu Taniguchi, and Tak W. Mak |
Title | Targeted Disruption of IRF-1 or IRF-2 Results in Abnormal Type I IFN Gene Induction and Aberrant Lymphocyte Development |
Journal | Cell |
Volume | 75 |
Page | 83-97 |
Year | 1993 |
PMID | 8402903 |
Author | Terada, K., Ueno, S., Yomogida, K., Imai, T., Kiyonari, H., Takeda, N., Yano, M., Abe, S., Aizawa, S., & Mori, M. |
Title | Expression of Tom34 splicing isoforms in mouse testis and knockout of Tom34 in mice. |
Journal | J. Biochem. |
Volume | 133 |
Page | 625-631 |
Year | 2003 |
PMID | 12801914 |
Disease name, Applicable field | Immunology |