CARD ID | 2935 | |
Type of strain | Targeted mutant. | |
Strain name | B6D2-Spaca6em2Osb | |
Internal Code | Spaca6 KO | |
Submitter | Ikawa Masahito | |
Submitter affiliation or code | Animal Resource Center for Infectious Diseases Research Institute for Microbial Diseases Osaka University | |
Stock Type | ||
Material Transfer Conditions |
Consent to us
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again. |
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Production method | in-house breeding | |
Origin (In-house) | Organization | |
Organization code | ||
Developer | ||
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Spaca6 |
Gene name | sperm acrosome associated 6 |
Allele symbol | Spaca6em2Osb |
Allele name | sperm acrosome associated 6; endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University |
MGI | MGI:1922452, |
Chromosome | 17 (10.50) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
OMIM |
Author | Taichi Noda , Yonggang Lu , Yoshitaka Fujihara , Seiya Oura , Takayuki Koyano , Sumire Kobayashi , Martin M Matzuk , Masahito Ikawa |
Title | Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice |
Journal | Proc Natl Acad Sci U S A . |
Volume | 26;117(21) |
Page | 11493-11502 |
Year | 2020 |
PMID |
Disease name, Applicable field |