CARD R-BASE



Mouse strain


Strain information

CARD ID 240
Type of strain Transgenic.
Strain name BXD-Tg(Hpoc-OSF1)
Internal Code Bone-rich mouse, HPoc-Hosf1-6
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Kyoto Pref. Univ, Med., RINDG, DBMG
Organization code
Developer Harufumi Masuda & T.Hashimoto-Gotoh
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol OSF1(=PTN)
Gene name Pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)(Human)
Allele symbol
Allele name
MGI
Chromosome Unknown ,
Gene classification Gene to express(transgenic)
Method
OMIM OMIM ID: 162095 Human Gene Symbol: PTN,

PCR Primer 1
primerA 5'(GAAAATTTGCAGCTGCCTTC)3' OSF_U246
primerB 3'(AACTCGTAGACTGAAGACC)5' TGL542


References

Author Haruchika Masuda, Atsushi Tasujimura, Makoto Yoshioka, Yuji Arai, Yoshinori Kuboki, Tsunehiro Mukai, Toshitaka Nakamura, Hajime Tsuji, Masao Nakagawa, and Tamotsu Hashimoto-Gotoh
Title Bone Mass Loss Due to Estrogen Deficiency Is Compensated in Transgenic Mice Overexpressing Human Osteoblast Stimulating Factor-11
Journal BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Volume 238
Page 528-533
Year 1997
PMID 9299545
Author Hashimoto-Gotoh, T., Masuda, H., Yamaguchi, M., Tsujimura, A., Ohnishi, H., Imai, S., Inoue, K., Nakamura, T., Hirasawa, T. and Nakagawa, M.
Title Feasibility of gene therapy using human OSF1 against osteoporosis
Journal Osteoporosis Japan
Volume 9
Page 5-7
Year 2001
PMID


Disease , Applicable field information

Disease name, Applicable field Metabolism






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