CARD ID | 473 | |
Type of strain | Targeted mutant. | |
Strain name | B6;CB-Spink3tm1Imeg | |
Internal Code | B6;CB-Spink3tm1Imeg | |
Submitter | Ken-ichi YAMAMURA | |
Submitter affiliation or code | Center for Animal Resources and Development Kumamoto University | |
Stock Type | ||
Material Transfer Conditions |
Consent to us
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Production method | in-house breeding | |
Origin (In-house) | Organization | Institute of Molecular Embryology and Genetics, Kumamoto University |
Organization code | Imeg | |
Developer | Masaki Ohmuraya | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Spink 3 |
Gene name | serine protease inhibitory Kazal type 3 |
Allele symbol | Spink3tm1Imeg |
Allele name | serine protease inhibitory Kazal type 3, targeted mutation 1 |
MGI | |
Chromosome | 18 , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
OMIM | OMIM ID: 167790 Human Gene Symbol: SPINK1, |
Author | Ohmuraya M, Hirota M, Araki M, Mizushima N,Matsui M, Mizumoto T, Haruna K, Kume S, Takeya M, Ogawa M, Araki K, Yamamura K. |
Title | Autophagic cell death of pancreatic acinar cells in serine protease inhibitor kazal type 3-deficient mice. |
Journal | Gastroenterology |
Volume | Aug;129(2) |
Page | 696-705 |
Year | 2005 |
PMID | 16083722 |
Disease name, Applicable field | Physiology |