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CARD Mouse Bank


Mouse strain


Strain information

CARD ID 324
Type of strain Spontaneous/Chemical induced mutant.
Strain name B6EiC3H-a/A Egfrwa2 Wnt3avt
Internal Code waved-2, B6EiC3H a/A-Egfrwa2Wnt3avt
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method From other organizations
Origin (In-house) Organization
Organization code
Developer
Origin (From other organizations) Organization The Jackson Laboratory
Organization code
Developer
Year introduced 2000 / 8
Introduced Generation
Remarks


Gene information

Gene symbol Wnt3a
Gene name Wingless-related MMTV integration site 3A
Allele symbol Wnt3avt
Allele name Wnt3a, vestigial
MGI MGI:98956,
Chromosome 11 (119.0cM) ,
Gene classification Other gene(mutant etc.)
Method
GO Gene Ontology
OMIM OMIM ID: 606359 Human Gene Symbol: WNT3A,
Gene symbol Egfr
Gene name Epidermal growth factor receptor
Allele symbol Egfrwa2
Allele name Egfr, waved 2
MGI MGI:95294,
Chromosome 11 (119.0cM) ,
Gene classification Other gene(mutant etc.)
Method
GO Gene Ontology
OMIM OMIM ID: 131550 Human Gene Symbol: EGFR,
Gene symbol a
Gene name nonagouti
Allele symbol A
Allele name A, C3H allele
MGI MGI:87853,
Chromosome 2 ,
Gene classification Other gene(mutant etc.)
Method
GO Gene Ontology
OMIM OMIM ID: 600201 Human Gene Symbol: ASIP,

PCR Primer 1
primerA 5'(TTGTG,GGTGG,CCTCC,TCTTC,ATAGTG)3'
primerB 5'(AAACG,CCGAT,CTTCC,AGGTA,GTTCA,TGCC)3'


References

Author KERRY J. FOWLER, FRANCESCA WALKER, WARREN ALEXANDER, MARGARET L. HIBBS, EDOUARD C. NICE, RALPH M. BOHMER, G. BRUCE MANN, CASSANDRA THUMWOOD, ROSEMARIE MAGLITTO, JANINE A. DANKS, RUNJEN CHETTY, ANTONY W. BURGESS, AND ASHLEY R. DUNN
Title A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation
Journal Proc. Natl. Acad. Sci. USA
Volume 92
Page 1465-1469
Year 1995
PMID 7533293


Disease , Applicable field information

Disease name, Applicable field






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