CARD R-BASE



Mouse strain


Strain information

CARD ID 387
Type of strain Transgenic., Targeted mutant.
Strain name B6;129-Ednrbtm1Ywa Tg(DBH-Ednrb)Ywa
Internal Code ENRB•Tg, B6;129-Ednrbtm1Ywa Tg(DBH-Ednrb)Ywa
Submitter Kato Masashi
Submitter affiliation or code Nagoya University Graduate School of Medicine Department of Occupational and Environmental Health
Stock Type
Material Transfer Conditions Consent to us
Production method From other organizations
Origin (In-house) Organization
Organization code
Developer
Origin (From other organizations) Organization Yanagisawa Masashi
Organization code Ywa
Developer The University of Texas
Year introduced 2003 / 10
Introduced Generation F1
Remarks


Gene information

Gene symbol Ednrb
Gene name endothelin receptor type B
Allele symbol
Allele name
MGI MGI:102720,
Chromosome
Gene classification Gene to express(transgenic)
Method Electroporation
GO Gene Ontology
OMIM OMIM ID: 131244 Human Gene Symbol: EDNRB,
Gene symbol Ednrb
Gene name endothelin receptor type B
Allele symbol
Allele name
MGI MGI:102720,
Chromosome 14 ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation
GO Gene Ontology
OMIM OMIM ID: 131244 Human Gene Symbol: EDNRB,

PCR Primer 1
primerA 5'(ctt ggg tgg aga ggc tat tc)3'
primerB 5'(agg tga gat gac agg aga tc)3'


References

Author Cheryl E. Gariepy, S. Clay Williams, James A. Richardson, Robert E. Hammer, and Masashi Yanagisawa
Title Transgenic Expression of the Endothelin-B Receptor Prevents Congenital Intestinal Aganglionosis in a Rat Model of Hirschsprung Disease
Journal J. Clin. Invest.
Volume 102
Page 1092-1101
Year 1998
PMID 9739043
Author Kiminori Hosoda, Robert E. Hammer, James A. Richardson, Amy Greenstein Baynash, Jason C. Cheung, Adel Giaid, and Masashi Yanagisawa
Title Targeted and Natural (Piebald-Lethal) Mutations of Endothelin-B Receptor Gene Produce Megacolon Associated with Spotted Coat Color in Mice
Journal Cell
Volume 79
Page 1267-1276
Year 1994
PMID 8001159


Disease , Applicable field information

Disease name, Applicable field Dermatology, cancer






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