CARD R-BASE



Mouse strain


Strain information

CARD ID 571
Type of strain Transgenic.
Strain name C57BL/6-Tg(CLCNKB-WNK4D564A
Internal Code mutant WNK4 transgenic mice, C57BL/6-Tg(CLCNKB-WNK4564A
Submitter Unknown Unknown
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method in-house breeding
Origin (In-house) Organization Tokyo Medical & Dental University
Organization code none
Developer Uchida Shinichi
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol WNK4
Gene name human WNK4 (lysine deficient protein kinase 4), D564A(Aan aspartic acid-to-alanine substitution at codon 564)
Allele symbol
Allele name
MGI
Chromosome Unknown ,
Gene classification Gene to express(transgenic)
Method MicroInjection
OMIM OMIM ID: 601844 Human Gene Symbol: WNK4,

PCR Primer 1
hWNK4seqPr2(tg-se) 5'-ATC GTC CGC TTC TAT GAT TC-3'
hWNK4R(tg-an) 5'-TCG CAC TTG AGA TCC CGG TG-3'


References

Author Kozue Yamauchi, Sung-Sen Yang, Akihito Ohta, Eisei Sohara, Tatemitsu Rai, Sei Sasaki, Shinichi Uchida
Title Apical localization of renal K channel was not altered in mutant WNK4 transgenic mice
Journal Biochemical and Biophysical Research Communications
Volume 332
Page 750-755
Year 2005
PMID 15907795


Disease , Applicable field information

Disease name, Applicable field Physiology






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