CARD ID | 2201 | |
Type of strain | Transgenic. | |
Strain name | C57BL/6Slc-Tg(NSE-betaCTFV717F,NSE-PS1P267S) | |
Internal Code | C105F/PS1P267S | |
Submitter | Akira Kakizuka | |
Submitter affiliation or code | Graduate School of Biostudies, Kyoto University | |
Stock Type | ||
Material Transfer Conditions |
Consent to us
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|
Production method | in-house breeding | |
Origin (In-house) | Organization | Graduate School of Biostudies, Kyoto University |
Organization code | ||
Developer | Akira Kakizuka | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | PS1(P267S) |
Gene name | HA-tagged full-length mutant presenilin 1 (P267S) |
Allele symbol | |
Allele name | |
MGI | |
Chromosome | Unknown , |
Gene classification | Gene to express(transgenic) |
Method | MicroInjection |
OMIM |
Gene symbol | betaCTF(V717F) |
Gene name | FLAG-tagged C-terminal portion of human betaCTF with Indiana mutation (V717F) |
Allele symbol | |
Allele name | |
MGI | |
Chromosome | Unknown , |
Gene classification | Gene to express(transgenic) |
Method | MicroInjection |
OMIM |
FLAG-C105F | GACTACAAGGACGACGATGACAAGGG |
C105F-genotyping primer(as) | TGCATCTGCTCAAAGAACTTGTAGG |
NSE-seq(s) | CAAGGCTGGTCCTCATCCAT |
NSE-seq(as) | GTCCTCGTCCTCATAGTACT |
hPS1-LC(s) | TTCGACTCCAGCAGGCATATCTC |
hPS1-LC(as) | AAGTGGACCTTTCGGACACAA |
Author | Norio Sasaoka, Megumi Sakamoto, Shoko Kanemori, Michiru Kan, Chihiro Tsukano, Yoshiji Takemoto, Akira kakizuka |
Title | Long-term Oral Administration of Hop Flower Extracts Mitigates Alzheimer Phenotypes in Mice |
Journal | PLOS ONE |
Volume | 9 |
Page | |
Year | 2014 |
PMID |
Disease name, Applicable field | Neurobiology |