CARD R-BASE



Mouse strain


Strain information

CARD ID 3289
Type of strain Targeted mutant.
Strain name Rad18tm1Stat
Internal Code Rad18-/- C57BL6/J
Submitter Satoshi Tateishi
Submitter affiliation or code IMEG, Kumamoto Univ.
Stock Type
Material Transfer Conditions No condition
Production method in-house breeding
Origin (In-house) Organization IMEG, Kumamoto University
Organization code
Developer Satoshi Tateishi, Ph.D
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Rad18
Gene name RAD18 E3 ubiquitin protein ligase; targeted mutation 1
Allele symbol Rad18tm1
Allele name RAD18 E3 ubiquitin protein ligase; targeted mutation 1,
MGI MGI:1890476,
Chromosome
Gene classification Targeted or trapped gene(knockout etc.)
Method
OMIM

PCR Primer 2
Rad18 WT fw 5-CCATATCTCCTGTGTCTTCCACCTCAAAGA-3
Rad18 WT rv 5-ACTTTAGTATCCAGTTTCATAGTGGATGTA-3
Rad18 Mut 5-TGATGATCTATTAAACCAATAAAGATGTCC-3


References

Author Tanoue Y, Toyoda T, Sun J, Mustofa MK, Tateishi C, Endo S, Motoyama N, Araki K, Wu D, Okuno Y, Tsukamoto T, Takeya M, Ihn H, Vaziri C, Tateishi S.
Title Differential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure
Journal
Volume
Page
Year 2018
PMID 29859927


Disease , Applicable field information

Disease name, Applicable field Dermatology, cancer, Cell biology, Development






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