CARD ID | 2091 | |
Type of strain | Targeted mutant. | |
Strain name | B6;129-Rab8atm1Rab8btm1 | |
Internal Code | Rab8ab DKO | |
Submitter | - - | |
Submitter affiliation or code | - | |
Stock Type | ||
Material Transfer Conditions |
Consent to us
|
|
Production method | in-house breeding | |
Origin (In-house) | Organization | |
Organization code | ||
Developer | ||
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks | Rab8a+/-; Rab8b-/- |
Gene symbol | Rab8b |
Gene name | Rab8b, member RAS oncogene |
Allele symbol | Rab8btm1 |
Allele name | Rab8b, member RAS oncogene, targeted mutation 1 |
MGI | MGI:2442982, |
Chromosome | 9 (36.17) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
OMIM |
Gene symbol | Rab8a |
Gene name | Rab8a, member RAS oncogene |
Allele symbol | Rab8atm1 |
Allele name | Rab8a, member RAS oncogene, targeted mutation 1 |
MGI | MGI:96960, |
Chromosome | 8 (34.84) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
OMIM |
8a genotype E | tgg ctt atg gca tat ctg ctg g |
8a genotype A | aag cag gcc tca act cac tga gat c |
8a genotype E | tgg ctt atg gca tat ctg ctg g |
8a genotype R | gcc aag ttt ggg gca tag tta c |
8bWT-S | gtt gga cat ctc ttc acc tat gc |
8bNull-AS | cag agc ctg aga agg tgc aat g |
Author | Takashi Sato, Tomohiko Iwano, Masataka Kunii, Shinji Matsuda, Rumiko Mizuguchi, Yongwook Jung, Haruo Hagiwara, Yoshihiro Yoshihara, Michisuke Yuzaki, Reiko Harada and Akihiro Harada |
Title | Rab8a and Rab8b are essential for multiple apical transport pathways but insufficient for ciliogenesis |
Journal | Journal of Cell Science |
Volume | |
Page | |
Year | in press |
PMID |
Author | Sato T, Mushiake S, Kato Y, Sato K, Sato M, Takeda N, Ozono K, Miki K, Kubo Y, Tsuji A, Harada R, Harada A. |
Title | The Rab8 GTPase regulates apical protein localization in intestinal cells. |
Journal | Nature |
Volume | 448 |
Page | 366-369 |
Year | 2007 |
PMID |
Disease name, Applicable field | Physiology, Anatomy, Cell biology, Neurobiology, Metabolism, Digestive Disorders |