CARD R-BASE



Mouse strain


Strain information

CARD ID 644
Type of strain Targeted mutant.
Strain name B6;CB-A4galttm1/Card
Internal Code Gb3KO
Submitter Koichi Furukawa
Submitter affiliation or code
Stock Type
Material Transfer Conditions Consent to us
Production method From other organizations
Origin (In-house) Organization
Organization code
Developer
Origin (From other organizations) Organization Naoki Takeda
Organization code Card
Developer Center for Animal Resources and Development
Year introduced 2003 / 4
Introduced Generation F1
Remarks


Gene information

Gene symbol A4galt
Gene name alpha 1,4-galactosyltransferase
Allele symbol
Allele name
MGI
Chromosome 15 (E2) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method Electroporation, MicroInjection
OMIM

PCR Primer 1
Neo-F1 CGT GAT ATT GCT GAA GAG CTT GGC GGC GAA
77KO-R1 GAA CTC ATG CTT GCG CTC GAA GGC TAG GAA


References

Author Tetsuya Okuda, Noriyo Tokuda, Shin-ichiro Numata, Masafumi Ito, Michio Ohta, Kumiko Kawamura, Joelle Wiels, Takeshi Urano, Orie Tajima, Keiko Furukawa, and Koichi Furukawa
Title Targeted Disruption of Gb3/CD77 Synthase Gene Resulted in the Complete Deletion of Globo-series Glycosphingolipids and Loss of Sensitivity to Verotoxins
Journal J. Biol. Chem.
Volume 281
Page 10230-10235
Year 2006
PMID


Disease , Applicable field information

Disease name, Applicable field Physiology, Development, Immunology, cancer, Metabolism






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