CARD ID | 2034 | |
Type of strain | Targeted mutant. | |
Strain name | C57BL/6-Hbegf tm1 | |
Internal Code | HBhz | |
Submitter | Unknown Unknown | |
Submitter affiliation or code | ||
Stock Type | ||
Material Transfer Conditions |
Consent to us
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Production method | in-house breeding | |
Origin (In-house) | Organization | Osaka University, Research Institute for Microbial Diseases |
Organization code | ||
Developer | Eisuke Mekada | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Hbegf |
Gene name | heparin-binding EGF-like growth factor |
Allele symbol | Hbegftm1 |
Allele name | heparin-binding EGF-like growth factor, targeted mutation 1 |
MGI | MGI:96070, |
Chromosome | 18 (19.46 ) , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | |
OMIM |
Intron3 Fw3 | CAT GGG GTT GTG ACT CTC CT |
Intron3 Rev3 | AGC CTG CAC ACA CAA AAG TG |
GFP Fwd | CAA GCA GAT CCT GAA GAA CA |
GFP Rev | GAA CAT CTC CTC GAT CAG GT |
Author | Tomoko Ichise1, Satoshi Adachi1, Minako Ohishi1, Masahito Ikawa2, Masaru Okabe2, Ryo Iwamoto1, and Eisuke Mekada |
Title | Humanized gene replacement in mice reveals the contribution of cancer stroma-derived HB-EGF to tumor growth |
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PMID |
Disease name, Applicable field |