CARD R-BASE



Mouse strain


Strain information

CARD ID 3010
Type of strain Targeted mutant.
Strain name BRJ-Ins2em1Kuma
Internal Code BRJ(BALB/c;Rag2-/-;Jak3-/-); Ins2Kuma
Submitter Kume Shoen
Submitter affiliation or code -
Stock Type
Material Transfer Conditions Consent to us
For non-profit, please cite the following publication. Sakano D, Inoue A, Enomoto T, Imasaka M, Okada S, Yokota M, Koike M, Araki K, Kume S. Insulin2 Q104del (Kuma) Mutant Mice Develop Diabetes with Dominant Inheritance, Sci, Reports 2020. 10(1):12187 doi: 10.1038/s41598-020-68987-z. For profit-making organization, MTA is required.
Production method in-house breeding
Origin (In-house) Organization Tokyo Institute of Technology
Organization code
Developer Shoen Kume
Origin (From other organizations) Organization
Organization code
Developer
Year introduced
Introduced Generation
Remarks


Gene information

Gene symbol Ins2
Gene name insulin II
Allele symbol Ins2em1Kuma
Allele name insulin II; endonuclease-mediated mutation 1,
MGI MGI:96573,
Chromosome 7 (88.00) ,
Gene classification Targeted or trapped gene(knockout etc.)
Method
OMIM



References

Author Airi Inoue, Takayuki Enomoto, Mai Imasaka, Seiji Okada, Mutsumi Yokota, Masato Koike, Kimi Araki, Shoen Kume
Title Insulin2 Q104del (Kuma) Mutant Mice Develop Diabetes with Dominant Inheritance
Journal Scientific Reports
Volume 10(1)
Page 12187
Year 2020
PMID


Disease , Applicable field information

Disease name, Applicable field Metabolism






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