CARD ID | 589 | |
Type of strain | Targeted mutant. | |
Strain name | ICR;129S4-Pargtm2Ncc/Csk | |
Internal Code | , ICR;129S4-Pargtm2Ncc/Csk | |
Submitter | Unknown Unknown | |
Submitter affiliation or code | ||
Stock Type | ||
Material Transfer Conditions |
Consent to us
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Production method | in-house breeding | |
Origin (In-house) | Organization | Chugai Research Institute for Medical Science Inc., National Cancer Center Research Institute |
Organization code | Csk, Ncc | |
Developer | Kou-ichi Jishage, Mitsuko Masutani | |
Origin (From other organizations) | Organization | |
Organization code | ||
Developer | ||
Year introduced | ||
Introduced Generation | ||
Remarks |
Gene symbol | Parg |
Gene name | Poly (ADP-ribose) glycohydrolase |
Allele symbol | Pargtm2Ncc |
Allele name | Parg,National Cancer Center Research Institute |
MGI | MGI:1347094, |
Chromosome | 14 , |
Gene classification | Targeted or trapped gene(knockout etc.) |
Method | Electroporation |
OMIM | OMIM ID: 603501 Human Gene Symbol: PARG, |
Author | Atsushi Shibata, Nobuo Kamada, Ken-ichi Masumura, Takehiko Nohmi, Shizuko Kobayashi, Hirobumi Teraoka, Hitoshi Nakagama, Takashi Sugimura, Hiroshi Suzuki and Mitsuko Masutani |
Title | Parp-1 deficiency causes an increase of deletion mutations and insertions/ rearrangements in vivo after treatment with an alkylating agent |
Journal | Oncogene |
Volume | 24 |
Page | 1328-1337 |
Year | 2005 |
PMID | 15608683 |
Author | MITSUKO MASUTANI, HIROSHI SUZUKI, NOBUO KAMADA, MIHO WATANABE, OTOYA UEDA, TADASHIGE NOZAKI, KOU-ICHI JISHAGE, TAKESHI WATANABE, TETSURO SUGIMOTO, HITOSHI NAKAGAMA, TAKAHIRO OCHIYA, AND TAKASHI SUGIMURA |
Title | Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes |
Journal | Proc. Natl. Acad. Sci. USA |
Volume | 96 |
Page | 2301-2304 |
Year | 1999 |
PMID | 10051636 |
Disease name, Applicable field | Metabolism, Development |